OTS186935 is a novel and potent inhibitor of protein methyltransferase SUV39H2 (Suppressor of variegation 3-9 homolog 2) with an IC50 of 6.49 nM. SUV39H2 , also known as KMT1B, is a member of the SUV39 subfamily of lysine methyltransferases (KMTs). SUV39H2 results in heterochromatin formation and transcriptional repression.
纯度:≥98%
CAS:2093400-18-9