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Icotinib Hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Icotinib Hydrochloride图片
CAS NO:1204313-51-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
BPI-2009H
产品介绍

生物活性

Icotinib hydrochloride是一种有效的特异性表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI),IC(50)为5 nM,包括EGFR(L858R),EGFR(L861Q),EGFR(T790M)和EGFR的突变体(T790M,L858R)。

化学数据

目录号A13718
作用机制Inhibitor (抑制剂)
M. Wt427.88
FormulaC22H22ClN3O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1204313-51-8
SynonymsBPI-2009H
SMILESC#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.37 mL116.86 mL233.71 mL
0.5 mM4.67 mL23.37 mL46.74 mL
1 mM2.34 mL11.69 mL23.37 mL
5 mM0.47 mL2.34 mL4.67 mL

*The above data is based on the productmolecular weight 427.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.