Rotigaptide, formerly known as GAP-486; ZP-123, is a gap junction modulator potentially for the treatment of ventricular tachycardia and atrial. References: Ng FS, Kalindjian JM, Cooper SA, Chowdhury RA, Patel PM, Dupont E, Lyon AR, Peters NS. Enhancement of Gap Junction Function During Acute Myocardial Infarction Modifies Healing and Reduces Late Ventricular Arrhythmia Susceptibility. JACC Clin Electrophysiol. 2016 Oct;2(5):574-582. PubMed PMID: 27807593; PubMed Central PMCID: PMC5076465.
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CAS:355151-12-1