19-Hydroxybufalin is a bufadienolide and the 18-hydorxylated form of bufalin, which is a novel and potent inhibitor of steroid receptor coactivator 3 (SRC-3) with anticancer, anti-inflammatory and antinociceptive activity. It is a naturally occurring digoxin-like immunoreactive component isolated from the Chinese medicine Chan Su. It exerts anticancer activity by inducing cell death through the ROS-mediated RIP1/RIP3/PARP-1 pathways.
纯度:≥98%
CAS:39844-86-5