AG28262 is a VEFG-2 inhibitor. AG28262 causes an increase in serum ALT, due in part to both gene up-regulation. References: Fuentealba C, Bera M, Jessen B, Sace F, Stevens GJ, Trajkovic D, Yang AH,
Evering W. Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine
aminotransferase gene expression and enzymatic activity in the rat liver. Comp
Hepatol. 2011 Aug 17;10:8. doi: 10.1186/1476-5926-10-8. PubMed PMID: 21846403;
PubMed Central PMCID: PMC3173283.
纯度:≥98%
CAS:638216-89-4