Description: Propranolol (also known as AY-64043, ICI-45520, NCS-91523) is a potent, competitive and non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. It blocks bothh β1 and β2 adrenergic receptors. Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase C-/D-mediated DAG production.
References: Mol Pharmacol. 1996 Jan;49(1):198-206.
Related CAS #: 525-66-6 (free base) 318-98-9 (HCl)
纯度:≥98%
CAS:525-66-6