R-84760 is a κ-opioid receptor agonist potentially for the treatment of pain. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in the central nervous system; and a part of the mechanism of the antinociceptive effect of R-84760 is activation of the descending noradrenergic pathway. References: Ohsawa M, Kamei J. Modification of kappa-opioid receptor agonist-induced antinociception by diabetes in the mouse brain and spinal cord. J Pharmacol Sci. 2005 May;98(1):25-32. PubMed PMID: 15879680.

纯度：≥98%

CAS：157824-23-2