| CAS NO: | 26095-59-0 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| Molecular Weight (MW) | 563.57 |
|---|---|
| Formula | C29H43BrN2O4 |
| CAS No. | 26095-59-0 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 113 mg/mL (200.5 mM) |
| Water: 113 mg/mL (200.5 mM) | |
| Ethanol: 113 mg/mL (200.5 mM) | |
| SMILES | O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-] |
| Synonyms | SP-63; Octylonium bromide; SP 63; SP63; |
| In Vitro | In vitro activity: Otilonium bromide is a quaternary ammonium compound whose spasmolytic action, selective on the distal gastrointestinal tract, is mainly due to its direct myolytic properties. This drug modifies Ca2+ fluxes from extracellular and intracellular pools in the intestinal smooth muscle and is poorly absorbed, thus it exerts its action locally, without any considerable systemic effect. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Arch Int Pharmacodyn Ther. 1983 Aug;264(2):305-23; Aliment Pharmacol Ther. 1998 Oct;12(10):1003-10. |
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