Demeclocycline calcium (Detravis; Ledermycin), the calcium salt of demeclocycline, is a protein translation inhibitor and calpain inhibitor of the tetracycline antibiotic class. It is a semisynthetic tetracycline antibiotic isolated from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.

纯度：≥98%

CAS：17146-81-5