RR-11a analogue is a potent and selective inhibitors of asparaginyl endopeptidases (AE) (Legumain), with IC50 of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively. References: Gotz MG, et al. Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens. J Med Chem. 2008 May 8;51(9):2816-32.

纯度：≥98%

CAS：685543-66-2