Thiostrepton is thiazole-based cyclic peptide isolated from Streptomyces and is active against gram-positive bacteria. Thiostrepton degrades mutant p53 by eliciting an autophagic response in SW480 cells. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at
regulatory regions of genes governing cell cycle may impact cell
proliferation.
纯度:≥98%
CAS:1393-48-2