SRI37892 is a frizzled-7 (Fzd7) inhibitor which inhibits LRP6 phosphorylation, downregulates the level of cytosolic free β-catenin, and functionally represses breast cancer cell viability and colony formation. SRI37892 targets the transmembrane domain of FZD7, thereby blocking the WNT signal transmission.
纯度:≥98%
CAS:1030769-75-5