AZ084 is a potent, selective, allosteric and orally bioavailable active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. References: Connolly S, et al. Orally bioavailable allosteric CCR8 antagonists inhibit dendritic cell, T cell and eosinophil migration. Biochem Pharmacol. 2012 Mar 15;83(6):778-87.
纯度:≥98%
CAS:929300-19-6