Acotiamide hydrochloride trihydrate (YM-443; Z-338) is a potent, orally bioactive and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia. It is approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.Acotiamide monohydrochloride trihydrate enhances acetylcholine released by enteric neurons through muscarinic receptor antagonism and acetylcholinesterase (AChE) inhibition, thereby enhancing gastric emptying and gastric accommodation. It acts as an acetylcholinesterase inhibitor.

纯度：≥98%

CAS：773092-05-0