A-779 is a peptide antagonist of the Mas receptor, formerly known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 = 0.3 nM in a radioligand binding assay). A-779 attenuates the potentiation of bradykinin by captopril in rats. References: Banday AA, Diaz Diaz A, Lokhandwala M. Kidney Dopamine D1-like Receptors and Angiotensin 1-7 Interaction Inhibits Renal Sodium Transporters. Am J Physiol Renal Physiol. 2019 Aug 14. doi: 10.1152/ajprenal.00135.2019. [Epub ahead of print] PubMed PMID: 31411069.
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CAS:159432-28-7