WWL229 is a selective Ces3 inhibitor. It acts by inhibiting recombinant Ces3 but not Ces1f, ABHD6 or other tested serine hydrolases, and recapitulating the effects of WWL113 in adipocytes. References: Soni KG, Lehner R, Metalnikov P, O'Donnell P, Semache M, Gao W, Ashman K, Pshezhetsky AV, Mitchell GA. Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase. J Biol Chem. 2004 Sep 24;279(39):40683-9. Epub 2004 Jun 25. PubMed PMID: 15220344.
纯度:≥98%
CAS:1338575-28-2