UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor potentially for the treatment of atopic dermatitis. UR-1505 acts by means of a specific mechanism inhibiting T cell activation depending on T cell receptor signaling pathway. Furthermore, the antiproliferative effects of UR-1505 are not a consequence of decreased cell viability. References: Vives R, Pontes C, Sarasa M, Millier A. Safety and Activity of UR-1505 in Atopic Dermatitis: A Randomized, Double-blind Phase II Exploratory Trial. Clin Ther. 2015 Sep 1;37(9):1955-65. doi: 10.1016/j.clinthera.2015.06.005. PubMed PMID: 26163200.

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CAS：651331-92-9