Pironetin is a natural α-tubulin-binding agent with potent antiproliferative activity. It acts by inhibiting cell division by forming a covalent adduct with α-tubulin. References: Huang DS, Wong HL, Georg GI. Synthesis and evaluation of C2 functionalized analogs of the α-tubulin-binding natural product pironetin. Bioorg Med Chem Lett. 2017 Nov 11. pii: S0960-894X(17)31059-4. doi: 10.1016/j.bmcl.2017.10.057. [Epub ahead of print] PubMed PMID: 29138028.
纯度:≥98%
CAS:151519-02-7