ZWM026 is a multi-target inhibitor, and an indolocarbazoles analogue derived from mangrove in coastal marine wetland. ZWM026 exhibits selectivity and reversibility against T790M mutant over wild-type EGFR in naturally occurring NSCLC cells and constructed NIH-3T3 cells. References: Song X, Qi X, Wang Q, Zhu W, Li J. A novel multi-target inhibitor harboring selectivity of inhibiting EGFR T790M sparing wild-type EGFR. Am J Cancer Res. 2017 Sep 1;7(9):1884-1898. eCollection 2017. PubMed PMID: 28979811; PubMed Central PMCID: PMC5622223.
纯度:≥98%