RL71 is a sselective inhibitor of SERCA2, specially binding to SERCA2 at a novel site, suppressing the Ca2+-ATPase activity of SERCA2, inducing apoptosis and downregulating Akt. References: Martey O, Nimick M, Taurin S, Sundararajan V, Greish K, Rosengren RJ. Styrene maleic acid-encapsulated RL71 micelles suppress tumor growth in a murine xenograft model of triple negative breast cancer. Int J Nanomedicine. 2017 Oct 4;12:7225-7237. doi: 10.2147/IJN.S148908. eCollection 2017. PubMed PMID: 29042771; PubMed Central PMCID: PMC5634372.
纯度:≥98%
CAS:1195795-93-7