PF-956980 is a pecific JAK3 inhibitor, reversing the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells. References: Field SD, Arkin J, Li J, Jones LH. Selective Downregulation of JAK2 and JAK3 by an ATP-Competitive pan-JAK Inhibitor. ACS Chem Biol. 2017 May 19;12(5):1183-1187. doi: 10.1021/acschembio.7b00116. Epub 2017 Mar 22. PubMed PMID: 28318222.

纯度：≥98%

CAS：1262832-74-5