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PF-04859989 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF-04859989 HCl图片
CAS NO:177943-33-8
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍

PF-04859989 HCl is a novel, selective, irreversible and brain-penetrant inhibitor of kynurenine amino transferase II (KAT II) with the potential for the treatment of cognitive impairment associated with schizophrenia and other psychiatric disorders. It is cyclic hydroxamic acid identified from a high-throughput screen. PF-04859989 acts by forming a covalent adduct with the enzyme cofactor, pyridoxal phosphate (PLP), in the active site. PF-04859989 is capable of reducing brain kynurenic acid by 50% at a dose of 10 mg/kg (sc).

纯度:≥98%

CAS:177943-33-8