PET-16 is a HSP70 inhibitor. Growth of multiple myeloma (MM) tumor cells under hypoxic conditions has no effect on the ability of PET-16 to be cytotoxic. References: Bailey CK, Budina-Kolomets A, Murphy ME, Nefedova Y. Efficacy of the HSP70 inhibitor PET-16 in multiple myeloma. Cancer Biol Ther. 2015;16(9):1422-6. doi: 10.1080/15384047.2015.1071743. Epub 2015 Jul 15. PubMed PMID: 26176532; PubMed Central PMCID: PMC4622955.
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CAS:34387-64-9