Memantine Hydrochloride is the hydrochloride salt of memantine, a low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system, preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist. References: Sahu A, Narayanam M, Kurmi M, Ladumor MK, Singh S. Quantitation of memantine hydrochloride bulk drug and its tablet formulation using proton nuclear magnetic resonance spectrometry. Magn Reson Chem. 2016 Feb 28. doi: 10.1002/mrc.4421. [Epub ahead of print] PubMed PMID: 26923624.

纯度：≥98%

CAS：41100-52-1