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Apcin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apcin图片
CAS NO:300815-04-7
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

Apcin is a ligand of Cdc20 and a potent and competitive inhibitor of the E3 ligase activity anaphase-promoting complex/cyclosome (APC/C). It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. Apcin occupes the D-box-binding pocket on the side face of the WD40-domain and can prolong mitosis.

纯度:≥98%

CAS:300815-04-7