PD 135158 is a Selective cholecystokinin type B (CCKB)/gastrin receptor agonist. In studies, PD- 135158 stimulates lipase release from isolated rat pancreatic acini dose dependently in a biphasic manner, with identical efficacy but lower potency compared to cholecystokinin octapeptide (CCK-8). PD 135158 is classified into Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, Psychotropic Drugs, and Tranquilizing Agents. References: Josselyn SA, Franco VP, Vaccarino FJ. PD-135158, a CCKB receptor antagonist, microinjected into the nucleus accumbens and the expression of conditioned rewarded behavior. Neurosci Lett. 1996 May 10;209(2):85-8. PubMed PMID: 8761988. 2: Hocker M, Hughes J, Folsch UR, Schmidt WE. PD 135158, a CCKB/gastrin receptor antagonist, stimulates rat pancreatic enzyme secretion as a CCKA receptor agonist. Eur J Pharmacol. 1993 Sep 21;242(1):105-8. PubMed PMID: 7901038.

纯度：≥98%

CAS：130325-35-8