PD 109488 is a metabolite of quinapril. PD 109488, otherwise known as Quinapril Diketopiperazine, is a analogue of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling. References:
纯度:≥98%
CAS:103733-49-9