OSU-2S Hydrochloride is a FTY720 analogue which lacks immunosuppressive properties, but exhibits strong anti-tumour activity in several haematological and solid tumour models. References: Mani R, Chiang CL, Frissora FW, Yan R, Mo X, Baskar S, Rader C, Klisovic R, Phelps MA, Chen CS, Lee RJ, Byrd JC, Baiocchi R, Lee LJ, Muthusamy N. ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo. Exp Hematol. 2015 Sep;43(9):770-4.e2. doi: 10.1016/j.exphem.2015.04.008. Epub 2015 Apr 29. PubMed PMID: 25937048.
纯度:≥98%
CAS:1351056-65-9