Ornithine-methotrexate is a ornithine analogue of methotrexate; inhibitors of dihydrofolate reductase. This decreases the tetrahydrofolate pool which then decreases synthesis of thymidyate and then inhibits DNA synthesis. References: Kempton RJ, Black AM, Anstead GM, Kumar AA, Blankenship DT, Freisheim JH. Lysine and ornithine analogues of methotrexate as inhibitors of dihydrofolate reductase. J Med Chem. 1982 Apr;25(4):475-7. PubMed PMID: 7069726.

纯度：≥98%

CAS：80407-73-4