APX001 is a prodrug of APX-001A, the first-in-class inhibitor of the fungal protein Gwt1. References: Zhao M, Lepak AJ, VanScoy B, Bader JC, Marchillo K, Vanhecker J, Ambrose PG, Andes DR. In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model. Antimicrob Agents Chemother. 2018 Jan 29. pii: AAC.02542-17. doi: 10.1128/AAC.02542-17. [Epub ahead of print] PubMed PMID: 29378706.
纯度:≥98%
CAS:1169701-00-1