Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors such as Brown-Pearce carcinoma. In clinical trials, it was found to be effective in treating patients with malignant pleural effusion and cancer of the head and neck. However, it was fairly toxic to hemopoietic organs. References: Su-yin C, Hsiu-fang Y, Pin H. Absorption, distribution and excretion of C14-AT-581 in animals. Chin Med J (Engl). 1976 Nov;2(6):441-4. PubMed PMID: 828876. 2: Yang JL, Lu FL, Wang LJ, Xu B. [The therapeutic effect of O-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (ocaphane, AT-581) on intracerebral growth of Brown-Pearce carcinoma in rabbits (author's transl)]. Yao Xue Xue Bao. 1981 Dec;16(12):881-5. Chinese. PubMed PMID: 7340381. 3: Yang JL, Hsu B. [Studies on the combined chemotherapy of o-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (AT-581) and operation in the treatment of Brown-Pearce carcinoma in the rabbit]. Yao Xue Xue Bao. 1966 Feb;13(2):113-8. Chinese. PubMed PMID: 5952402. 4: YANG JL, HSU B. [THERAPEUTIC EFFECT OF AT-581 ON THE BROWN-PEARCE CARCINOMA IN RABBITS AND ITS INFLUENCE ON MITOSIS OF THE TUMOR CELLS]. Yao Xue Xue Bao. 1965 Apr;12:235-41. Chinese. PubMed PMID: 14321745.

纯度：≥98%

CAS：2185-98-0