NSC-658497 is an inhibitor of SOS1-Ras interaction. It acts by dose-dependently inhibiting SOS1 GEF activity. References: Evelyn CR, Duan X, Biesiada J, Seibel WL, Meller J, Zheng Y. Rational design of small molecule inhibitors targeting the Ras GEF, SOS1. Chem Biol. 2014 Dec 18;21(12):1618-28. doi: 10.1016/j.chembiol.2014.09.018. Epub 2014 Nov 20. PubMed PMID: 25455859; PubMed Central PMCID: PMC4272618.

纯度：≥98%

CAS：909197-38-2