NPS2390 is a group I mGlu antagonist. It exhibits noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket. References: Xue Z, Song Z, Wan Y, Wang K, Mo L, Wang Y. Calcium-sensing receptor antagonist NPS2390 attenuates neuronal apoptosis though intrinsic pathway following traumatic brain injury in rats. Biochem Biophys Res Commun. 2017 Apr 29;486(2):589-594. doi: 10.1016/j.bbrc.2017.03.097. Epub 2017 Mar 20. PubMed PMID: 28336431.

纯度：≥98%

CAS：226878-01-9