NP-G2-044 is an orally bioavailable inhibitor of the protein fascin, with potential antineoplastic activity. Upon orally bioavailable administration, NP-G2-044 targets and binds to fascin, thereby preventing the interaction of fascin with actin filaments, thereby preventing actin bundling and filopodia formation. By preventing actin cytoskeletal reorganization, the dynamic changes in cell shape that are necessary for tumor cell migration and invasion to occur are impaired, and tumor cell migration and metastasis are inhibited. References:
纯度:≥98%
CAS:1807454-59-6