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TMP 269
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TMP 269图片
CAS NO:1314890-29-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
10mM * 1mL in DMSO电议

产品名称
TMP-269,TMP269
产品介绍

生物活性

TMP 269是一种有效的选择性IIa类HDAC抑制剂,对HDAC4,HDAC5,HDAC7和HDAC9的IC50分别为157 nM,97 nM,43 nM和23 nM。

化学数据

目录号A14128
作用机制Inhibitor (抑制剂)
M. Wt514.52
FormulaC25H21F3N4O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1314890-29-3
SynonymsTMP-269,TMP269
SMILESO=C(c1cccc(c1)c1noc(n1)C(F)(F)F)NCC1(CCOCC1)c1scc(n1)c1ccccc1

溶解度

In vitroDMSO89 mg/mL (172.97 mM)
WaterInsoluble
EthanolWarmed: 2 mg/mL (3.88 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.44 mL97.18 mL194.36 mL
0.5 mM3.89 mL19.44 mL38.87 mL
1 mM1.94 mL9.72 mL19.44 mL
5 mM0.39 mL1.94 mL3.89 mL

*The above data is based on the productmolecular weight 514.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.