规格: | ≥98% |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
1g | 电议 |
Description: Azatadine HCl, a drug used for treating allergic rhinitis and chronic urticaria, is a potent histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively. Azatadine delays the onset of dyspnea-induced by aerosolized histamine, acetylcholine and serotonin in the conscious guinea-pig with PD50 of 0.01 mg/kg, 0.739 mg/kg and 0.86 mg/kg. Azatadine protects conscious guinea-pigs against death induced by the intravenous injection of histamine with oral PD50 of 0.009 mg/kg in guinea-pig and 0.22 mg/kg in mice References: Agents Actions. 1974 Oct;4(4):264-70; Clin Pharmacokinet. 1991 Nov;21(5):372-93.
纯度:≥98%