您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > N-(Azido-PEG4)-biocytin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
N-(Azido-PEG4)-biocytin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-(Azido-PEG4)-biocytin图片
CAS NO:2055042-70-9
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍
N-(Azido-PEG4)-biocytin is a PEG-based linker used in the synthesis of PROTACs. It is a biotin PEG analog containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible (covalent) amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.