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Azido-PEG3-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Azido-PEG3-acid图片
CAS NO:1056024-94-2
规格:≥98%
包装与价格:
包装价格(元)
250mg电议
500mg电议
1g电议
2g电议

产品介绍

Azido-PEG3-acid (N3-PEG3-CH2CH2COOH) is a novel and potent PEG (polyethyleneglycol) analogue used as a PROTAC linker for the synthesis of BI-3663, BI-4216 and BI-0319. As a PEG-based linker, Azido-PEG3-acid is also used as a non-cleavable 3 unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is composed of an azido group, PEG spacer, and carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) forming a stable amide bond. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

纯度:≥98%

CAS:1056024-94-2