Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation. References: Starkov AA, Fiskum G. Myxothiazol induces H(2)O(2) production from mitochondrial respiratory chain. Biochem Biophys Res Commun. 2001 Mar 2;281(3):645-50. PubMed PMID: 11237706.
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CAS:76706-55-3