MSAB is a novel and potent inhibitor of Wnt/β-catenin signaling with anticancer activity. It acts by binding to β-catenin, promoting its degradation, and specifically downregulating Wnt/β-catenin target genes. The Wnt/β-catenin signaling pathway plays a major role in tissue homeostasis, and its dysregulation can lead to various human diseases. Aberrant activation of β-catenin is oncogenic and is a critical driver in the development and progression of human cancers.
纯度:≥98%
CAS:173436-66-3