Restorer of wild-type p53 conformation/cellular function
CAS：72835-26-8
分子式：C8H9NO4
分子量：183.16
纯度：98%
存储：Store at -20°C

Background:

Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent mannerin vitro(IC₅₀= 10μM).