CAS NO: | 136085-37-5 |
规格: | 98% |
分子量: | 396.43 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
Extracted?from?Campanulaceae Codonopsis pilosula;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:136085-37-5
分子式:C20H28O8
分子量:396.43
纯度:98%
存储:Store at -20°C
Background:
Lobetyolin is derived from Codonopsis pilosula and has antioxidative effect.
Lobetyolin is derived from Codonopsis pilosula and has antioxidative effect. MUC5AC gene expression induced by phorbol 12-myristate 13-acetate (PMA) from NCI-H292 cells is inhibited by pretreatment with Lobetyolin, lobetyol or methyl linoleate. Lobetyolin does not affect PMA-induced MUC5AC production from NCI-H292 cells. The amounts of mucin in the cells of Lobetyolin-treated cultures are 100±25%, 487±33%, 524±38%, 411±24%, and 402±45% for control, 10 ng/mL of PMA alone, PMA plus Lobetyolin 1 μM, PMA plus Lobetyolin 10 μM, and PMA plus Lobetyolin 100 μM, respectively[1].
参考文献:
[1]. Yoon YP, et al. Effects of Lobetyolin, Lobetyol and Methyl linoleate on Secretion, Production and Gene Expression of MUC5AC Mucin from Airway Epithelial Cells. Tuberc Respir Dis (Seoul). 2014 Nov;77(5):203-8.