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bpV(pic)(potassium hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
bpV(pic)(potassium hydrate)图片
CAS NO:148556-27-8
规格:98%
分子量:367.3
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM).
CAS:148556-27-8
分子式:C6H4NO7V.2K [2H2O]
分子量:367.3
纯度:98%
存储:Store at -20°C

Background:

bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.