EMT inhibitor-2 (Compound 1) 抑制由免疫细胞释放的物质如 IL-1β 和 TGF-β 诱导的上皮-间质转化 (EMT)。EMT inhibitor-2 抑制CYP3A4 睾酮和 CYP2C9，IC50 分别为 49.72 和 5.54 μM。
CAS：2232228-60-1
分子式：C24H26N2O8
分子量：470.47
纯度：98%
存储：Store at -20°C

Background:

EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively[1].

[1]. Youn, Byung Soo, et al. Substituted chromenes for treatment of fibrosis or non-alcoholic steatohepatitis. US10370364.