JG-98是一种热休克蛋白70(Hsp70)抑制剂,具有抗癌活性。
CAS:1456551-16-8
分子式:C24H21Cl2N3OS3
分子量:534.54
纯度:98%
存储:Store at -20°C
Background:
JG-98 is a heat shock protein 70 (Hsp70) Inhibitor with anti-cancer activities[1][2].
Heat shock protein 70[1]
JG-98 inhibits the breast cancer cell lines MDA-MB-231 and MCF-7 with EC50 values of 0.4 and 0.7 μM, respectively[1].
[1]. Yaglom JA, et al. Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and findingsynergistic drug combinations. Sci Rep. 2018 Feb 14;8(1):3010.