Microtubule inhibitor 1 是一种抗癌药物,能够抑制微管聚合,其在肿瘤细胞中的IC50 为 9-16 nM。
CAS:2305668-80-6
分子式:C21H19NO3
分子量:333.38
纯度:98%
存储:Store at -20°C
Background:
Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity, with an IC50 value of 9-16 nM in cancer cells[1].
Microtubule polymerization[1].
[1]. Li W, et al. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity. J Med Chem. 2019 Jan 24;62(2):993-1013.