E3 ligase Ligand-Linker Conjugates 38 包含用于 E3 泛素连接酶的 cIAP 配体和 linker。E3 ligase Ligand-Linker Conjugates 38 可通过 PROTAC 技术合成降解剂。
CAS:2095244-52-1
分子式:C46H64N4O12S2
分子量:929.15
纯度:98%
存储:Store at -20°C
Background:
E3 ligase Ligand-Linker Conjugates 38 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 38 can be used to design PROTAC degrader[1].
cIAP1
[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.