Altretamine hydrochloride 是一种烷化剂 (alkylator),具有抗肿瘤活性。
CAS:2975-00-0
分子式:C9H19ClN6
分子量:246.74
纯度:98%
存储:Store at -20°C
Background:
Altretamine hydrochloride is an alkylating antineoplastic agent.
Altretamine hydrochloride is an antineoplastic agent[1].
Altretamine (100, 133 mg/kg, ip.) in combination with Irofulven, increases the antitumor effect in mice bearing MV522 cells[1].
[1]. Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63(1):19-26.