E3 ligase Ligand-Linker Conjugates 33 包含用于 E3 泛素连接酶的 cIAP 配体和 linker。E3 ligase Ligand-Linker Conjugates 33 可通过 PROTAC 技术合成降解剂。
CAS：1239943-19-1
分子式：C35H43N3O7
分子量：617.73
纯度：98%
存储：Store at -20°C
Background:
E3 ligase Ligand-Linker Conjugates 33 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 33 can be used to design PROTAC degrader[1].
cIAP1
[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.
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