The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis.
CAS：331770-21-9
分子式：C23H20N4O3
分子量：400.4
纯度：98%
存储：Store at -20°C

Background:

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.